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1

For the record

Lindahl, Maria, Danilova, Tatiana, Palm, Erik, Lindholm, Päivi, Võikar, Vootele, Hakonen, Elina, Ustinov, Jarkko, Andressoo, Jaan-Olle, Harvey, Brandon K., Otonkoski, Timo, Rossi, Jari, Saarma, Mart

Journal:

Year:

2006

Language:

english

File:

PDF, 90 KB

english, 2006

2

Chromosomal alterations in human pancreatic endocrine tumors

Erik Stumpf, Yan Aalto, Anders Höög, Magnus Kjellman, Timo Otonkoski, Sakari Knuutila, Leif C. Andersson

Journal:

Genes, Chromosomes and Cancer

Year:

2000

Language:

english

File:

PDF, 77 KB

english, 2000

3

A syndrome with multiple malformations, mental retardation, and ACTH deficiency

Eero Kajantie, Timo Otonkoski, Sirpa Kivirikko, Mirja Somer

Journal:

American Journal of Medical Genetics Part A

Year:

2004

Language:

english

File:

PDF, 198 KB

english, 2004

4

Mechanisms of beta cell death during restricted and unrestricted enterovirus infection

Suvi Rasilainen, Petri Ylipaasto, Merja Roivainen, Luc Bouwens, Risto Lapatto, Tapani Hovi, Timo Otonkoski

Journal:

Journal of Medical Virology

Year:

2004

Language:

english

File:

PDF, 418 KB

english, 2004

5

Mechanisms of coxsackievirus B5 mediated β-cell death depend on the multiplicity of infection

Suvi Rasilainen, Petri Ylipaasto, Merja Roivainen, Risto Lapatto, Tapani Hovi, Timo Otonkoski

Journal:

Journal of Medical Virology

Year:

2004

Language:

english

File:

PDF, 475 KB

english, 2004

6

Distinct differentiation characteristics of individual human embryonic stem cell lines

Milla Mikkola, Cia Olsson, Jaan Palgi, Jarkko Ustinov, Tiina Palomaki, Nina Horelli-Kuitunen, Sakari Knuutila, Karolina Lundin, Timo Otonkoski, Timo Tuuri

Journal:

BMC Developmental Biology

Year:

2006

Language:

english

File:

PDF, 2.12 MB

english, 2006

7

Restricted ethnic diversity in human embryonic stem cell lines

Laurent, Louise C, Nievergelt, Caroline M, Lynch, Candace, Fakunle, Eyitayo, Harness, Julie V, Schmidt, Uli, Galat, Vasiliy, Laslett, Andrew L, Otonkoski, Timo, Keirstead, Hans S

Journal:

Year:

2010

Language:

english

File:

PDF, 233 KB

english, 2010

8

Gene Expression Signatures of Seven Individual Human Embryonic Stem Cell Lines

Heli Skottman, Milla Mikkola, Karolina Lundin, Cia Olsson, Anne-Marie Strömberg, Timo Tuuri, Timo Otonkoski, Outi Hovatta, Riitta Lahesmaa

Journal:

Year:

2005

Language:

english

File:

PDF, 428 KB

english, 2005

9

GAD65 Antigen Therapy in Recently Diagnosed Type 1 Diabetes Mellitus

Ludvigsson, Johnny, Krisky, David, Casas, Rosaura, Battelino, Tadej, Castaño, Luis, Greening, James, Kordonouri, Olga, Otonkoski, Timo, Pozzilli, Paolo, Robert, Jean-Jacques

Journal:

Boston Medical and Surgical Journal

Year:

2012

Language:

english

File:

PDF, 621 KB

english, 2012

10

Proliferation and plasticity of human beta cells on physiologically occurring laminin isoforms

Meenal Banerjee, Ismo Virtanen, Jaan Palgi, Olle Korsgren, Timo Otonkoski

Journal:

Molecular and Cellular Endocrinology

Year:

2012

Language:

english

File:

PDF, 1.12 MB

english, 2012

11

Laminin-511 expression is associated with the functionality of feeder cells in human embryonic stem cell culture

Heidi Hongisto, Sanna Vuoristo, Alexandra Mikhailova, Riitta Suuronen, Ismo Virtanen, Timo Otonkoski, Heli Skottman

Journal:

Stem Cell Research

Year:

2012

Language:

english

File:

PDF, 1.32 MB

english, 2012

12

Dose-dependent cysteine-mediated protection of insulin-producing cells from damage by hydrogen peroxide

Suvi Rasilainen, Jenni M. Nieminen, Anna-Liisa Levonen, Timo Otonkoski, Risto Lapatto

Journal:

Biochemical Pharmacology

Year:

2002

Language:

english

File:

PDF, 419 KB

english, 2002

13

Laminin isoforms in human embryonic stem cells: synthesis, receptor usage and growth support

Sanna Vuoristo, Ismo Virtanen, Minna Takkunen, Jaan Palgi, Yamato Kikkawa, Patricia Rousselle, Kiyotoshi Sekiguchi, Timo Tuuri, Timo Otonkoski

Journal:

Journal of Cellular and Molecular Medicine

Year:

2009

Language:

english

File:

PDF, 1.01 MB

english, 2009

14

Transcription factor GATA-6 is expressed in the endocrine and GATA-4 in the exocrine pancreas

Ilkka Ketola, Timo Otonkoski, Mari-Anne Pulkkinen, Hannele Niemi, Jaan Palgi, Christina M. Jacobsen, David B. Wilson, Markku Heikinheimo

Journal:

Molecular and Cellular Endocrinology

Year:

2004

Language:

english

File:

PDF, 608 KB

english, 2004

15

Maturation of in vitro-generated human islets after transplantation in nude mice

Ru Gao, Jarkko Ustinov, Olle Korsgren, Milla Mikkola, Karolina Lundin, Timo Otonkoski

Journal:

Molecular and Cellular Endocrinology

Year:

2007

Language:

english

File:

PDF, 4.62 MB

english, 2007

16

Weighing up β-cell mass in mice and humans: Self-renewal, progenitors or stem cells?

Neil A. Hanley, Karen Piper Hanley, Päivi J. Miettinen, Timo Otonkoski

Journal:

Molecular and Cellular Endocrinology

Year:

2008

Language:

english

File:

PDF, 396 KB

english, 2008

17

A new subtype of autosomal dominant diabetes attributable to a mutation in the gene for sulfonylurea receptor 1

Hanna Huopio, Timo Otonkoski, Ilkka Vauhkonen, Frank Reimann, Frances M Ashcroft, Markku Laakso

Journal:

Year:

2003

Language:

english

File:

PDF, 116 KB

english, 2003

18

Dominantly inherited form of hyperinsulinism caused by a gene mutation in the sulfonylurea receptor 1

Timo Otonkoski, Hanna Huopio, Frank Reimann, Rebecca Ashfield, Markku Laakso, Frances Ashcroft

Journal:

Diabetes Research and Clinical Practice

Year:

2000

Language:

english

File:

PDF, 110 KB

english, 2000

19

Carriers of an inactivating beta-cell K-ATP channel mutation have normally regulated insulin secretion

Hanna Huopio, Ilkka Vauhkonen, Jorma Komulainen, Leo Niskanen, Timo Otonkoski, Markku Laakso

Journal:

Diabetes Research and Clinical Practice

Year:

2000

Language:

english

File:

PDF, 107 KB

english, 2000

20

Transcription factor expression and hormone production in pancreatic AR42J cells

Jaan Palgi, Erik Stumpf, Timo Otonkoski

Journal:

Molecular and Cellular Endocrinology

Year:

2000

Language:

english

File:

PDF, 751 KB

english, 2000

21

Over- and Underdosage of SOX3 Is Associated with Infundibular Hypoplasia and Hypopituitarism

Kathryn S. Woods, Maria Cundall, James Turton, Karine Rizotti, Ameeta Mehta, Rodger Palmer, Jacqueline Wong, W.K. Chong, Mahmoud Al-Zyoud, Maryam El-Ali, Timo Otonkoski, Juan-Pedro Martinez-Barbera, Q

Journal:

The American Journal of Human Genetics

Year:

2005

Language:

english

File:

PDF, 6.62 MB

english, 2005

22

Physical Exercise–Induced Hypoglycemia Caused by Failed Silencing of Monocarboxylate Transporter 1 in Pancreatic β Cells

Timo Otonkoski, Hong Jiao, Nina Kaminen-Ahola, Isabel Tapia-Paez, Mohammed S. Ullah, Laura E. Parton, Frans Schuit, Roel Quintens, Ilkka Sipilä, Ertan Mayatepek, Thomas Meissner, Andrew P. Halestrap,

Journal:

The American Journal of Human Genetics

Year:

2007

Language:

english

File:

PDF, 789 KB

english, 2007

23

Lack of glucose-induced functional maturation during long-term culture of human fetal islet cells

Timo Otonkoski, Mikael Knip, Inés Wong, Olli Simell

Journal:

Year:

1991

Language:

english

File:

PDF, 446 KB

english, 1991

24

The IIIb isoform of fibroblast growth factor receptor 2 is required for proper growth and branching of pancreatic ductal epithelium but not for differentiation of exocrine or endocrine cells

Mari-Anne Pulkkinen, Bradley Spencer-Dene, Clive Dickson, Timo Otonkoski

Journal:

Mechanisms of Development

Year:

2003

Language:

english

File:

PDF, 589 KB

english, 2003

25

High-throughput karyotyping of human pluripotent stem cells

Riikka J. Lund, Tuomas Nikula, Nelly Rahkonen, Elisa Närvä, Duncan Baker, Neil Harrison, Peter Andrews, Timo Otonkoski, Riitta Lahesmaa

Journal:

Stem Cell Research

Year:

2012

Language:

english

File:

PDF, 694 KB

english, 2012

26

ErbB Signaling Regulates Lineage Determination of Developing Pancreatic Islet Cells in Embryonic Organ Culture

Huotari, Mari-Anne, Miettinen, Päivi J., Palgi, Jaan, Koivisto, Tarja, Ustinov, Jarkko, Harari, Daniel, Yarden, Yosef, Otonkoski, Timo

Journal:

Year:

2002

Language:

english

File:

PDF, 821 KB

english, 2002

27

Small Molecule Inhibitors Promote Efficient Generation of Induced Pluripotent Stem Cells From Human Skeletal Myoblasts

Trokovic, Ras, Weltner, Jere, Manninen, Tuula, Mikkola, Milla, Lundin, Karolina, Hämäläinen, Riikka, Suomalainen, Anu, Otonkoski, Timo

Journal:

Stem Cells and Development

Year:

2013

Language:

english

File:

PDF, 1.59 MB

english, 2013

28

Stem cells in the treatment of diabetes

Otonkoski, Timo, Gao, Ru, Lundin, Karolina

Journal:

Annals of Medicine

Year:

2005

Language:

english

File:

PDF, 243 KB

english, 2005

29

Activin A and Wnt-dependent specification of human definitive endoderm cells

Toivonen, Sanna, Lundin, Karolina, Balboa, Diego, Ustinov, Jarkko, Tamminen, Kaisa, Palgi, Jaan, Trokovic, Ras, Tuuri, Timo, Otonkoski, Timo

Journal:

Experimental Cell Research

Year:

2013

Language:

english

File:

PDF, 7.00 MB

english, 2013

30

MANF Is Indispensable for the Proliferation and Survival of Pancreatic β Cells

Lindahl, Maria, Danilova, Tatiana, Palm, Erik, Lindholm, Päivi, Võikar, Vootele, Hakonen, Elina, Ustinov, Jarkko, Andressoo, Jaan-Olle, Harvey, Brandon K., Otonkoski, Timo, Rossi, Jari, Saarma, Mart

Journal:

Year:

2014

Language:

english

File:

PDF, 3.30 MB

english, 2014

31

Patient-Specific Induced Pluripotent Stem Cell–Derived RPE Cells: Understanding the Pathogenesis of Retinopathy in Long-Chain 3-Hydroxyacyl-CoA Dehydrogenase Deficiency

Polinati, Padmini P., Ilmarinen, Tanja, Trokovic, Ras, Hyotylainen, Tuulia, Otonkoski, Timo, Suomalainen, Anu, Skottman, Heli, Tyni, Tiina

Journal:

Investigative Opthalmology & Visual Science

Year:

2015

Language:

english

File:

PDF, 808 KB

english, 2015

32

In vivo activation of the PI3K–Akt pathway in mouse beta cells by theEGFRmutation L858R protects against diabetes

Hakonen, Elina, Ustinov, Jarkko, Eizirik, Décio L., Sariola, Hannu, Miettinen, Päivi J., Otonkoski, Timo

Journal:

Year:

2014

Language:

english

File:

PDF, 4.01 MB

english, 2014

33

Integrative genomics and transcriptomics analysis of human embryonic and induced pluripotent stem cells

Laurila, Kirsti, Autio, Reija, Kong, Lingjia, Närvä, Elisa, Hussein, Samer, Otonkoski, Timo, Lahesmaa, Riitta, Lähdesmäki, Harri

Journal:

Year:

2014

Language:

english

File:

PDF, 1.40 MB

english, 2014

34

Rapid Genetic Analysis in Congenital Hyperinsulinism

Christesen, Henrik B.T., Brusgaard, Klaus, Alm, Jan, Sj&ouml, blad, Sture, Hussain, Khalid, Fenger, Claus, Rasmussen, Lars, Hovendal, Claus, Otonkoski, Timo, Jacobsen, Bendt Brock

Journal:

Hormone Research

Year:

2007

Language:

english

File:

PDF, 108 KB

english, 2007

35

A Novel Feeder-Free Culture System for Human Pluripotent Stem Cell Culture and Induced Pluripotent Stem Cell Derivation

Vuoristo, Sanna, Toivonen, Sanna, Weltner, Jere, Mikkola, Milla, Ustinov, Jarkko, Trokovic, Ras, Palgi, Jaan, Lund, Riikka, Tuuri, Timo, Otonkoski, Timo, Shioda, Toshi

Journal:

Year:

2013

Language:

english

File:

PDF, 3.85 MB

english, 2013

36

mtDNA Mutagenesis Disrupts Pluripotent Stem Cell Function by Altering Redox Signaling

Hämäläinen, Riikka H., Ahlqvist, Kati J., Ellonen, Pekka, Lepistö, Maija, Logan, Angela, Otonkoski, Timo, Murphy, Michael P., Suomalainen, Anu

Journal:

Year:

2015

Language:

english

File:

PDF, 3.01 MB

english, 2015

37

Insulin and Glucagon Secretory Responses to Arginine, Glue agon, and Theophylline During Perifusion of Human Fetal Islet-Like Cell Clusters*

OTONKOSKI, TIMO

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

1988

Language:

english

File:

PDF, 867 KB

english, 1988

38

Generation of iPSC line HEL47.2 from healthy human adult fibroblasts

Trokovic, Ras, Weltner, Jere, Otonkoski, Timo

Journal:

Stem Cell Research

Year:

2015

Language:

english

File:

PDF, 464 KB

english, 2015

39

Conditionally Stabilized dCas9 Activator for Controlling Gene Expression in Human Cell Reprogramming and Differentiation

Balboa, Diego, Weltner, Jere, Eurola, Solja, Trokovic, Ras, Wartiovaara, Kirmo, Otonkoski, Timo

Journal:

Stem Cell Reports

Year:

2015

Language:

english

File:

PDF, 4.22 MB

english, 2015

40

Generation of iPSC line HEL24.3 from human neonatal foreskin fibroblasts

Trokovic, Ras, Weltner, Jere, Otonkoski, Timo

Journal:

Stem Cell Research

Year:

2015

Language:

english

File:

PDF, 430 KB

english, 2015

41

Mechanisms of Coxsackievirus-Induced Damage to Human Pancreaticβ -Cells 1

Roivainen, Merja, Rasilainen, Suvi, Ylipaasto, Petri, Nissinen, Riikka, Ustinov, Jarkko, Bouwens, Luc, Eizirik, Décio L., Hovi, Tapani, Otonkoski, Timo

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

2000

Language:

english

File:

PDF, 1.65 MB

english, 2000

42

Developmental Gene Expression in the Human Fetal Pancreas

Mally, Martin I, Otonkoski, Timo, Lopez, Ana D, Hayek, Alberto

Journal:

Pediatric Research

Year:

1994

Language:

english

File:

PDF, 6.75 MB

english, 1994

43

Growth Factor-Mediated Proliferation and Differentiation of Insulin-Producing INS-1 and RINm5F Cells: Identification of Betacellulin as a Novel β-Cell Mitogen 1

Huotari, Mari-Anne, Palgi, Jaan, Otonkoski, Timo

Journal:

Year:

1998

Language:

english

File:

PDF, 212 KB

english, 1998

44

EGF- and TGF-α-Like Peptides in Human Fetal Gut

Miettinen, Paivi J, Perheentupa, Jaakko, Otonkoski, Timo, Lahteenmaki, Antti, Panula, Pertti

Journal:

Pediatric Research

Year:

1989

Language:

english

File:

PDF, 648 KB

english, 1989

45

Combined negative effect of donor age and time in culture on the reprogramming efficiency into induced pluripotent stem cells

Trokovic, Ras, Weltner, Jere, Noisa, Parinya, Raivio, Taneli, Otonkoski, Timo

Journal:

Stem Cell Research

Year:

2015

Language:

english

File:

PDF, 1.15 MB

english, 2015

46

New tools for experimental diabetes research: Cellular reprogramming and genome editing

Otonkoski, Timo

Journal:

Upsala Journal of Medical Sciences

Year:

2016

Language:

english

File:

PDF, 809 KB

english, 2016

47

Regulation of human pluripotent stem cell derived hepatic cell phenotype by 3D hydrogel models

Toivonen, Sanna Charlotta, Malinen, Melina, Küblbeck, Jenni, Petsalo, Aleksanteri, Urtti, Arto, Honkakoski, Paavo, Otonkoski, Timo

Journal:

Tissue Engineering Part A

Year:

2016

Language:

english

File:

PDF, 2.02 MB

english, 2016

48

MATURATION AND FUNCTION OF HUMAN FETAL PANCREATIC CELLS AFTER CRYOPRESERVATION1,2

BEATTIE, GILLIAN M., OTONKOSKI, TIMO, LOPEZ, ANA D., HAYEK, ALBERTO

Journal:

Transplantation Journal

Year:

1993

File:

PDF, 625 KB

1993

49

EGF receptor in pancreatic β-cell mass regulation

Miettinen, Päivi, Ormio, Päivi, Hakonen, Elina, Banerjee, Meenal, Otonkoski, Timo

Journal:

Biochemical Society Transactions

Year:

2008

Language:

english

File:

PDF, 131 KB

english, 2008

50

sept7b is required for the differentiation of pancreatic endocrine progenitors

Dash, Surjya Narayan, Hakonen, Elina, Ustinov, Jarkko, Otonkoski, Timo, Andersson, Olov, Lehtonen, Sanna

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 2.66 MB

english, 2016